Researchers are testing an exciting new method to grow human organs in space. Their goal is to develop liver tissue that could be used for transplants on Earth. This research is being conducted aboard the International Space Station (ISS), which orbits in a microgravity environment. The unique conditions of low-Earth orbit help address challenges scientists face when attempting to engineer tissues on Earth.
Tammy T Chang, the lead researcher, explains that liver tissues grown in space show better development and function compared to those cultured on Earth. This breakthrough could revolutionize liver transplantation by providing a new source of viable liver tissues for patients in need. The research team hopes that these space-grown tissues could one day serve as an alternative to traditional liver transplants.
However, the process doesn’t end in space. Scientists are exploring ways to preserve the tissues for safe transport back to Earth. One promising technique is called isochoric supercooling. It cools the tissues below freezing without causing damage, allowing them to be stored for longer periods.
Dr. Chang says that if these techniques are successful, they could pave the way for other biomedical applications. These include disease modeling, drug testing, and eventually, using entire organs grown in space for therapeutic purposes. This research marks an important step toward the future of medical treatments.
Photo caption: Four patented Tissue Orb bioreactors within spaceflight hardware. This configuration will be launched into space and installed into the International Space Station during the first flight experiment in February 2025.
Credit: Tammy T. Chang, MD PhD FACS
